The month of November is usually pretty good in Colorado, but planning to ride on a particular day can be hit or miss. If you build some flexibility into your schedule, then you should have a great time.
If you’re coming to Colorado through Kansas or Nebraska, there are a wide variety of trails between Morrison and Lyons – Hall Ranch in Lyons would be a nice warm up for Moab. If you are coming in from Texas or Oklahoma, Canon City would be good place to start.
Buffalo Creek is a little further west and I usually ride there at least once in November. It has some awesome trails and is definitely worth a stop.
Salida is a great town with fun trails that are usually rideable throughout the winter. I would absolutely plan on spending a little time there.
Fruita is on the Western Slope and usually a little dryer. Give yourself enough time to ride Kokopelli and 18 Road.
Have Fun!