Most women’s specific bikes (26ers at least) will seem to "fit" females better usually if they are smaller, like 5’3"-5’4" or shorter. But like brianW’s wife pointed out, everyone is different. Comfort is key though, for beginner women especially!
A "men’s" bike can work great with some tweaks like the saddle (a must!) and often a shorter stem and cranks can make a big difference. I would let her weigh in on the decision and go to a bike a shop where they are knowledgeable enough to help her out with the right size and fit. Good luck & happy riding!